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From Middle English mous, from Old English mÅ«s, from Proto-Germanic *mÅ«s, from Proto-Indo-European *muhâ‚‚s.

Full definition of mouse

(plural mice)

1893, Walter Besant, The Ivory Gate Chapter 2, At twilight in the summer there is never anybody to fearâ€”man, woman, or catâ€”in the chambers and at that hour the mice come out. They do not eat parchment or foolscap or red tape, but they eat the luncheon crumbs.

(informal) A member of the many small rodent and marsupial species resembling such a rodent.
A quiet or shy person.
(computing) (plural mice or, rarely, mouses) An input device that is moved over a pad or other flat surface to produce a corresponding movement of a pointer on a graphical display.
(boxing) Hematoma.
(nautical) A turn or lashing of spun yarn or small stuff, or a metallic clasp or fastening, uniting the point and shank of a hook to prevent its unhooking or straighening out.
(obsolete) A familiar term of endearment.
A match used in firing guns or blasting.

(intransitive) To move cautiously or furtively, in the manner of a mouse (the rodent) (frequently used in the phrasal verb to mouse around).
(intransitive) To hunt or catch mice (the rodents), usually of cats.
(transitive, nautical) To close the mouth of a hook by a careful binding of marline or wire.Captain Higgins moused the hook with a bit of marline to prevent the block beckets from falling out under slack.
(intransitive, computing) To navigate by means of a computer mouse.

1988, MacUser: Volume 4I had just moused to the File menu and the pull-down menu repeated the menu bar's hue a dozen shades lighter.
2009, Daniel Tunkelang, Faceted Search (page 35)Unlike the Flamenco work, the Relation Browser allows users to quickly explore a document space using dynamic queries issued by mousing over facet elements in the interface.