Pseudopseudohypoparathyroidism

Pronunciation

• RP IPA: /ËŒsjuː.dəʊˌsjuː.dəʊˌhaɪ.pəʊ.pær.əˈθaɪ.rɔɪd.ɪzÉ™m/
• US IPA: /ËŒsuː.doÊŠËŒsuː.doÊŠËŒhaɪ.poÊŠ.pær.əˈθaɪ.rɔɪd.ɪzÉ™m/

Origin

From -("false") + pseudohypoparathyroidism.

Full definition of pseudopseudohypoparathyroidism

Noun

1. (medicine) A mild inherited condition in which the sufferer has symptoms similar to those of pseudohypoparathyroidism.
• 2007, Dominique N. Long, Sarah McGuire, Michael A. Levine, Lee S. Weinstein, Emily L. Germain-Lee, Body Mass Index Differences in Pseudohypoparathyroidism Type 1a Versus Pseudopseudohypoparathyroidism May Implicate Paternal Imprinting of Gαs in the Development of Human Obesity, Journal of Clinical Endocrinology & Metabolism, Volume 92, no. 3, pages 1073-1079,Because Gαs is paternally imprinted in certain hormone target tissues, maternal inheritance of AHO leads to multihormone resistance type 1a (PHP1a), whereas paternal inheritance leads to AHO alone (pseudoPHP). Classically, the obesity in AHO is described as occurring similarly in both conditions.

Synonyms

• pseudoPHP

Related terms

• hypoparathyroidism
• pseudohypoparathyroidism