Refractory
Pronunciation
- UK IPA: /ɹɪˈfɹæk.təɹ.i/
Origin
From Latin refractÄrius ("obstinate"), from refractus, past participle of refringere ("to break up"). Originally refractary reanalysed after other adjectives in -ory
Full definition of refractory
Adjective
refractory
- Obstinate and unruly; strongly opposed to something.
- 1787, s:Author:Alexander Hamilton, s:The Federalist Papers Chapter s:The Federalist Papers/No. 16, ... in most instances attempts to coerce the refractory and disobedient have been the signals of bloody wars, ...
- 1836, Charles Dickens, , ,Mr. Weller knocked at the door, and after a pretty long interval—occupied by the party without, in whistling a tune, and by the party within, in persuading a refractory flat candle to allow itself to be lighted ...
- Not affected by great heat.
- Pure lime is extremely refractory, but readily fusible if any silex is brought in contact with it; ...
- (medicine) Difficult to treat.
- 1949, Albert Fields and John Hoesley, "Neck and Shoulder Pain", Calif. Med., 70(6):478–482.,Many of the vague and refractory cases of neck and shoulder pain and of migraine may be due to cervical disc disease.
- 1990, H. A. Ring et al, "Vigabatrin: rational treatment for chronic epilepsy", J. Neurol. Neurosurg.Psychiatry, 53(12):1051–1055,In 33 adult patients with long standing refractory epilepsy on treatment with one or two standard anti-convulsant drugs,
- (biology) Incapable of registering a reaction or stimulus.
- 1959, Nobusada Ishiko and Werner R. Loewenstein, "Electrical output of a receptor membrane", Science (journal), 1959, 130:1405-6,The production of a generator potential leaves a refractory state in the receptor membrane ...
- 1970, S.S. Barold et al, "Chest wall stimulation in evaluation of patients with implanted ventricular-inhibited demand pacemakers", Br. Heart J., 32(6):783–789,The ... delivery of external stimuli ... delineates the pacemaker refractory period after the emission of a pacing stimulus and after the sensing of a spontaneous beat.
Derived terms
Related terms
Noun
refractory
(plural refractories)- A material or piece of material, such as a brick, that has a very high melting point.