Zalcitabine

Origin

zal-, of origin, + citabine, variation of cytidine.

Full definition of zalcitabine

Noun

1. (pharmaceutical drug) The compound 2'-3'-dideoxycytidine, a nucleoside analog reverse transcriptase inhibitor, formerly used in antiretroviral therapy
• July 4, 1997, B. Autran et al., Positive Effects of Combined Antiretroviral Therapy on CD4 T Cell Homeostasis and Function in Advanced HIV Disease, Patients received 600 mg/day of ritonavir (Abbott Laboratories) for 14 days, after which were added 600 mg/day of zidovudine (Retrovir, Glaxo-Wellcome) and 6 mg/day of zalcitabine (Hivid, Roche) with treatment maintenance for 12 months.

Synonyms

• dideoxycytidine
• ddC