• Amphipathic

    Origin

    - + pathic + -

    Full definition of amphipathic

    Adjective

    amphipathic

    1. (chemistry) describing a molecule, such as a detergent, which has both hydrophobic and hydrophilic groups.
    2. (biochemistry) often refers to the surface(s) on a protein, particularly an alpha helix, where one surface of the alpha helix has hydrophilic amino acids and the opposite face has hydrophobic (or lipophilic) amino acids.
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